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Histamine, allergies and how you feel

Allergy season in Houston can leave you sneezing, foggy and worn out. Dr. Michael Ennis explains what histamine does, why the nervous system plays a role and how upper cervical care may fit alongside your physician's care.

Published April 18, 2024 · Updated October 1, 2026
Allergy Alert with Dr. Ennis

Why allergies hit so hard

Spring in Houston brings green trees, blooming flowers and, for many people, a runny nose and itchy eyes. Allergies can show up any time of year here, from tree and grass pollen to mold and dust. For some people, they’re a mild nuisance. For others, they take over.

Dr. Michael Ennis knows that feeling well. As a child, his allergies were severe enough to keep him from many everyday activities. His family tried everything, from shots and medications to surgeries. Chiropractic care became a turning point in his own health, and it shaped the career he chose. That experience is a big reason he cares so much about how the nervous system affects the way we feel.

What histamine does

Histamine is a natural chemical your body makes. It’s stored in certain immune cells, especially mast cells, which are common in the skin, nose, lungs and gut.

When your immune system sees something as a threat, these cells release histamine. In a true threat, that’s helpful. Histamine widens blood vessels, increases fluid and mucus and helps immune cells reach the area.

With allergies, the immune system overreacts to something that is usually harmless, like pollen or pet dander. The result is a histamine response that’s bigger than the situation calls for. That’s what causes many familiar symptoms:

  • Sneezing and a runny or stuffy nose
  • Itchy, watery eyes
  • An itchy throat or skin
  • Hives or swelling in some people

Histamine isn’t the only chemical involved in allergic reactions, but it’s one of the main ones.

How allergy medications work

Most people reach for an antihistamine when allergies flare. These medications work by blocking histamine from attaching to its receptors, which reduces symptoms like sneezing and itching. Other medications, such as nasal steroid sprays, calm inflammation in different ways.

These treatments help many people, and they’re an important tool. If you rely on them, keep using them as your physician or pharmacist recommends.

Where the nervous system comes in

Your immune system doesn’t work alone. It’s in constant communication with your nervous system. The brain and nerves help regulate inflammation, blood flow and how the body responds to stress, and immune cells can respond to nerve signals.

The brainstem, which passes through the top of your neck, is a key part of this communication network. It helps regulate many automatic functions, including breathing, heart rate and parts of the stress response.

This is where Dr. Ennis’s perspective comes in. Conventional allergy medications block the signals that lead to symptoms. His focus is different: supporting a nervous system that functions as well as possible, so the body is better able to respond to its environment in a balanced way.

Where NUCCA care fits

Let’s be clear about what NUCCA care is and isn’t. It is not an allergy treatment, and it isn’t a replacement for your allergist or your medication.

NUCCA upper cervical care focuses on the alignment of the atlas, the top bone in the neck. When the atlas is out of position, it can affect posture and tension in the area around the brainstem. Our goal is to restore balance to that area with a precise, gentle correction. There’s no twisting, popping or cracking.

Some patients tell us they feel better overall once their upper neck is balanced, including during allergy season. That’s an individual experience, not a promise, and research in this area is limited. You can learn more about our approach to whole-body wellness and how it fits with your other care.

Simple ways to ease allergy season

Alongside your doctor’s advice, a few everyday habits can help:

  • Check pollen counts and plan outdoor time when they’re lower.
  • Keep windows closed on high-pollen days and use air conditioning.
  • Shower and change clothes after spending time outdoors.
  • Wash bedding weekly in hot water.
  • Protect your sleep. Congestion and poor rest can leave you foggy and tired. Our page on sleep help covers more.
  • Pay attention to lingering fatigue. If you feel drained long after allergy season, our page on brain fog and fatigue may help, and it’s a good idea to check in with your doctor.

When to see a doctor right away

Seek emergency care immediately for trouble breathing, swelling of the lips, tongue or throat, wheezing, dizziness or fainting after exposure to an allergen. These can be signs of a severe allergic reaction.

Learn more about your nervous system

If you’d like to find out whether your upper neck is in balance, start with a $79 new patient visit at our Clear Lake office. Read more about NUCCA upper cervical care, or call (281) 218-7571 with any questions.

Watch the video

Allergies Alert! How Your Histamine Levels Drive How You Feel

Frequently asked questions

Can NUCCA care treat allergies?

No. NUCCA care doesn't treat allergies or replace allergy medication. Its goal is to restore balance to the upper neck, where the nervous system and brainstem meet. Because the nervous system helps regulate how the body responds to its environment, some patients feel their overall well-being improves. Please keep working with your physician or allergist on your allergy plan.

Should I stop my antihistamine if I start upper cervical care?

No. Keep taking your medications as prescribed. Antihistamines and other allergy treatments are an important part of managing symptoms for many people. Any change to your medication should be made only with the physician who prescribed it. Upper cervical care is meant to work alongside your physician's care, not replace it.

Why do allergies make me feel so tired and foggy?

Allergies affect more than your nose. Histamine and other chemicals released during an allergic reaction can contribute to fatigue, and congestion often disrupts sleep. Poor sleep, in turn, can leave you feeling foggy the next day. If tiredness or brain fog lingers beyond allergy season, talk with your doctor, since other causes may be involved.

Ready to discover what gentle, precise care feels like?

Start with a $79 first visit: a health history review, non-invasive exams, a one-on-one consultation and a clear plan with every cost explained up front.

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